UPDATE 2016: As we receive new information on Canadian
research, it will be posted here. We are awaiting research notification
from McGill University.
2015: HAMILTON GENERAL HOSPITAL
Assessment and Rehabilitation of Allodynia
This research focuses
on allodynia (painful sensitivity) and how it can
be measured and treated. Eligible participants:
- must be over
16 years of age and have a confirmed diagnosis of CRPS
- OR nerve damage
- OR recent hand
fracture (past 12 weeks).
In addition an 8
week therapy program will be offered for allodynia. Parking expenses
will be reimbursed.
To take part, please contact Tara
Packham, OT, Principal Investigator: email@example.com or TEL:
905 527 4322 ext. 46297
Research is by MacHANd
(McMaster Hand Arm and Nerve Research Network).
Please email Tara
Packham for further information. (PARC does not have more information.)
of a perfusion MRI technique to investigate longitudinal effects
of chronic pain on brain function
"The aim of
this study is to find a tool for evaluation of treatment success
in CRPS patients, Magnetic resonance imaging (MRI)
is a diagnostic tool in medicine that generates high quality imaging
of the human body without the use of x-rays. It can also provide
information regarding how the brain functions, which is referred
to as functional magnetic resonance imaging (fMRI). Changes in brain
function during the course of treatment will be studied to investigate
how such changes can reflect the success of treatment."
Research is done
at Lawson Institute at St. Joe's Hospital in London Ontario. Participants
will be reimbursed. For details, please email:
Mahsa Shokouhi PhD
Recovery from CRPS: a patients perspective"
McCabe CS RGN PhD
Royal Hospital for
Rheumatic Diseases, Bath UK
In July 2012, the CRPS Recovery Team began its research. It is a
team of doctors, researchers and patient research partners (PRPs)
who continue to work on the research data that is coming in. We
are studying how and why patients recover. Part
1 has already been submitted for publication.
PARC's Executive Director is a member of this 8 country, International
CRPS Recovery team. Part 2 continues in 2014.
Publication in 2016.
Two abstracts from
the research have been submitted for publication.
is sponsored by RSDSA of America.
Hamilton Inventory for CRPS.
PARC was pleased to sponsor our first local Canadian
Please note: this research
below has been completed. Special thanks to all who participated.
A research team from Hamilton Health Sciences and McMaster University
are developing an assessment tool that is specific to complex regional
pain syndrome. One part of the assessment was a questionnaire that
asked the person to rate their own symptoms and the impact those
symptoms had on their daily activities and relationships. We also
interviewed people who have experienced CRPS to assist us in this
Tara Packham, OT Reg.(Ont), MSc
Hamilton Health Sciences
Dr. Joy MacDermid, PT, PhD
Physiotherapist and Associate Professor
School of Rehabilitation Sciences, McMaster University
[This work was conducted with support from PARC: Promoting Awareness
of RSD CPRS.]
changes in CRPS are becoming well known. The European Journal of
Pain 2012 has recently published a study done by Jenny Lewis PhD
of Bath, UK entitled "Body Perception Disturbance."
PARC was able to donate a further $5,000 to Mc Gill
University to assist the NIRS studies at Montreal General Hospital.
The NIRS machine (laser) will be travelling to San Diego, CA this
winter to a busy pain clinic of CRPS patients at UCSD where space
and research personnel have been donated. Many thanks to the dedicated
Dr. Bennett who will travel and resume the study in California.
PARC's contribution will help make this happen. Please read about
the NIRS study below.
Dr. Terrence Corderre (left) and Dr Gary Bennett (right), of Mc
Gill University shown with the near-infrared spectrophotometer (NIRS)
that was purchased with the help of PARC, Great West Life Assurance
Company, and the family of Mr. Jeffrey Owens. The NIRS
machine has the unique ability to measure blood flow and oxygenation
in muscles non-invasively and painlessly via a laser light source
and light sensor placed on the skin over the muscle. Drs. Bennett
and Corderre are using the machine to test their theory that at
least CRPS patients have pain due to an injury to the capillary
blood vessels in a muscle.
PARC NOTE: With your help, PARC can continue to support the research
of these excellent scientists at Mc Gill.
RESEARCH PAPERS BY DRS. BENNETT AND/OR CODERRE
"Objectifying CRPS": Coderre
"Chronic Post-Ischemic Pain":
Coderre et al.pdf
This is only a partial list of research papers.
INTRODUCTION: DR. GARY BENNETT PhD
Gary J. Bennett, Ph.D., is Canada Senior Research Chair, Department
of Anesthesia and Faculty of Dentistry, McGill University in Montreal,
Canada. He earned his bachelor’s degree (Psychology) in 1970
from Rutgers University and his Ph.D. (Experimental Psychology)
from the Medical College of Virginia, Virginia Commonwealth University
in 1978. In the same year, he joined the Neurobiology and Anesthesiology
Branch (NAB), National Institute of Dental Research, National Institutes
of Health, as a Public Health Service Postdoctoral Fellow. He was
appointed to the permanent staff of NAB in 1979, and was made Chief
of the Neuropathic Pain and Pain Measurement Section in 1991. In
1996, he became Professor in the Department of Neurology at MCP
Hahnemann University in Philadelphia. He joined McGill University
He has served on the American Pain Society’s Board of Directors
and on the Editorial Board for Pain (1986-1999), the journal of
the International Association for the Study of Pain, and currently
serves on the Editorial Board for Pain Medicine, the journal of
the American Academy of Pain Medicine. He has served on the Board
of Directors of the Reflex Sympathetic Dystrophy Syndrome Association
of America, where he was Director of Research, and received their
Scientific Achievement Award in 2000. He was awarded the American
Pain Society’s Frederick W.L. Kerr Basic Science Research
Award in 1996, and the American Academy of Pain Medicine’s
Founder’s Award in 2001. For the past 25 years, his research
has focused on the mechanisms underlying normal and abnormal pain
sensations, and the pharmacological basis of pain control.
Currently, Dr. Bennett has returned to USA to further conduct research.
UPDATE: APRIL 2010:
PARC was able to donate $10,000 towards CRPS research at Mc Gill.
Please see the photo at the top of this page for details.
UPDATE: December 2008
Due to the RIDE TO CONQUER CRPS 2008 and the fine efforts of
Dr D.L. Shulman, PARC was able to donate $5,000 towards CRPS research.
We urge all of you who are interested in finding a cure for CRPS,
to support the research being done at McGill.
RESEARCH UPDATE: Aug. 22, 2008:
Dr G. Bennett,PhD, Sr. Research Chair, McGill University, and
Montreal General Hospital will be holding a conference in conjunction
RIDE TO CONQUER CRPS 2008 on July 28.
UPDATE: FEB 2007: Astra Zeneca has donated $2.5
million to a new lab at McGill University. Dr Magali Millecamps
is the post doctoral fellow studying CRPS under the supervision
of Dr Gary Bennett and Terry Cordere. Our hats are off to these
For more on McGill University please visit: McGill
RESEARCH PROJECTS AT MCGILL
FOR CRPS 2011
General Hospital Pain Center
- Sylvia Toupin or Laura Pallett
- TEL: 514 934 1934 ext 44348 or ext 42115
Complex Regional Pain
Syndrome Type I (RSD):
New data from the
clinic and the laboratory.
A Pain Forum presentation of the MUHC Pain
DATE: Monday, 28 July 2008
TIME: 1:00-4:30 PM
PLACE: Livingston Hall Lounge (Room L6-500)
Montreal General Hospital
1:00-1:05 Welcoming remarks (Gary J. Bennett, PhD;
1:05-1:45 CRPS-I: The clinical picture. (David L. Shulman,
MD CCFP FCFP DAAPM; Rothbart Pain Clinic, Toronto) RIDE
TO CONQUER CRPS 2008 STOP
1:45 -2:45 A new theory: Deep tissue microvascular pathology
as the cause of CRPS-I. (Terence J. Coderre, PhD; McGill
2:45-3:00 Health break
3:00-3:30 The role of the endothelins in CPIP pathology
(Magali. Millecamps, PhD, McGill University)
3:30-4:00 CRPS-I breakthroughs: New data from Boston and
Haifa (G. Bennett, PhD)
Many thanks to Gary Bennett PhD and colleagues for hosting the
successful and very informative CRPS conference on July 28 at Montreal
Why is CRPS research important?!
BULLETIN: New research has found
markers for CRPS. From Boston, a skin biopsy can now detect distal
nerve damage. From Haifa Israel, a saliva test can measure high
levels of LDH (lactate dehyrogenase), the same substance found in
heart attack victims. It also found high levels of albumin.
DUTCH RESEARCH: In a database
of 900,000 patients from 150 GPs in Holland, (specifically patients
who attend a doctor), the rate of occurrence has been established
as 26.2 in 100,000 patients.This is approximately 1 in every 4,000
UPDATE 2016: For updated research projects at
McGill University please follow this link:
McGill Pain Research
I KNOW WHAT YOU'RE THINKING...........
WHY SHOULD I PARTICIPATE?
McGill University is known around the world for its pain research.
First of all, the research being conducted will help the researchers
better understand the "puzzle of CRPS/RSD", what causes
it, and how it works in the body.
Secondly, the scientific knowledge gained from these studies
will lead to the development of better treatments for this painful,
neurological syndrome. New treatments are desperately needed.
MORE IMPORTANTLY,CRPS patients living in Canada will benefit
from new treatments first.
Thirdly, the researcher in question, Dr Bennett, has a great
deal of experience studying and testing patients since he has already
conducted quality CRPS/RSD research for over 25 years in United
Lastly, doing something NOW that will benefit you later, should
be considered as a very good reason to help this excellent researcher
gather his data.
PARC urges all Canadians to participate and we plan to offer ourselves
as subjects. What about you?